Details
| Product Name | C3 |
| Chinese Name | 补体C3单克隆抗体 |
| Alias | Acylation stimulating protein cleavage product; Acylation-stimulating protein cleavage product; AHUS5; ARMD9; ASP; ASP; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1 antibody C3 antibody C3a anaphylatoxin; CO3_HUMAN; Complement C3 alpha chain; Complement C3; Complement C3 beta chain; Complement C3 precursor; Complement C3b alpha chain; Complement C3c alpha' chain fragment 2; Complement C3c fragment; Complement C3d fragment; Complement C3f fragment; Complement C3g fragment; Complement component 3; Complement component 3 precursor; Complement component C3; Complement factor 3; CPAMD1; Plp. |
| literatures |
Specific References (1) | SLM-51535M has been referenced in 1 publications.
[IF=3.252] Ganggang Li. et al. Baicalin suppresses neuron autophagy and apoptosis by regulating astrocyte polarization in pentylenetetrazol-induced epileptic rats and PC12 cells. Brain Res. 2022 Jan;1774:147723 WB,IF ; Rat.
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| Research Area | immunology Neurobiology Signal transduction |
| Immunogen Species | Mouse |
| Clonality | Monoclonal |
| Clone NO. | B3N11 |
| React Species | Human, |
| Applications | WB=1:500-2000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| Theoretical molecular weight | 187kDa |
| Cellular localization | cytoplasmic |
| Form | Liquid |
| Concentration | 1mg/ml |
| immunogen | KLH conjugated synthetic peptide derived from human C3: 1301-1400/1663 |
| Lsotype | IgG1 |
| Purification | affinity purified by Protein G |
| Buffer Solution | 1M TBS(pH7.4) with 1% BSA, 3% Proclin300 and 50% Glycerol. |
| Storage | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
| Attention | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| Product Detail |
The complement factor C3 consists of an alpha and a beta chain. C3 is a central factor in the complement cascade. It is central to the alternative pathway that leads to the C3 convertase C3bBb. The classical mannose binding lectin activation pathway leads to the C3 convertase C4b2a. These convertases cleave C3 resulting in C3a and C3b. Further degradation leads to the formation of the alpha chain products C3d, C3g and C3c. C3 is an acute phase protein that is produced by a wide range of tissues, including renal epithelial cells and hepatocytes. Subcellular Location: Secreted. Tissue Specificity: Plasma. The acylation stimulating protein (ASP) is expressed in adiopocytes and released into the plasma during both the fasting and postprandial periods. Similarity: Contains 1 anaphylatoxin-like domain. Contains 1 NTR domain. SWISS: P01024 Gene ID: 718 Database links: Entrez Gene: 718 Human SwissProt: P01024 Human |
| Product Picture |
Sample:
Lane 1: Hela cell lysates Lane 2: HepG2 cell lysates Lane 3: K562 cell lysates Lane 4: CCRF-CEM cell lysates Lane 5: MDA-MB-453 cell lysates Primary: Anti-C3 (SLM-51535M) at 1/2000 dilution Secondary: IRDye800CW Goat Anti-Mouse IgG at 1/20000 dilution Predicted band size: 187 kD Observed band size: 145 kD |
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