Details
Product Name | GPR30, Alexa Fluor 680 conjugated |
Chinese Name | AF680标记的G protein-coupled receptor30抗体 |
Alias | G Protein Coupled Receptor 30; G-protein coupled receptor 30; G-protein coupled estrogen receptor 1; Membrane estrogen receptor; mER; Chemokine receptor-like 2; IL8-related receptor DRY12; Flow-induced endothelial G-protein coupled receptor 1; FEG-1; Lymphocyte-derived G-protein coupled receptor; LYGPR; GPCR-BR; CEPR; CMKRL2; DRY12; GPER. |
Research Area | Cell biology Neurobiology Signal transduction The cell membrane受体 G protein-coupled receptor G protein signal |
Immunogen Species | Rabbit |
Clonality | Polyclonal |
React Species | (predicted: Human, Mouse, Rat, ) |
Applications | IF=1:20-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
Theoretical molecular weight | 42kDa |
Cellular localization | The nucleus cytoplasmic The cell membrane Extracellular matrix |
Form | Liquid |
Concentration | 1mg/ml |
immunogen | KLH conjugated synthetic peptide derived from human GPR30: 21-120/375 <Extracellular> |
Lsotype | IgG |
Purification | affinity purified by Protein A |
Buffer Solution | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
Storage | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
Attention | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
Product Detail |
G protein-coupled receptors (GPRs, or GPCRs) contain 7 hydrophobic transmembrane domains embedded in hydrophilic intra- and extracellular loops and transduce a variety of hormone, endogenous peptide, and neurotransmitter signals into intracellular effects via G proteins. GRP30 is a member of this family and is an orphan receptor. GPR30 expression has been reported in brain, breast carcinoma, blood, bone marrow, CNS, heart, liver, lung, lymph node, placenta, and spleen. In brain, GPR30 is expressed as a 2.8 kb transcript in basal forebrain, frontal cortex, thalamus, hippocampus, caudate and putamen. However, unlike other known G protein-coupled receptors, GPR30 localizes to the endoplasmic reticulum, where it specifically binds estrogen and estrogen derivatives. SWISS: Q99527 Gene ID: 2852 Database links: Entrez Gene: 2852 Human Entrez Gene: 76854 Mouse Omim: 601805 Human SwissProt: Q99527 Human SwissProt: Q8BMP4 Mouse Unigene: 20961 Human Unigene: 389706 Mouse Unigene: 9806 Rat |
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