Anti-Cyclin G antibody_Primary Antibody_Antibody_SUNLONG BIOTECH CO., LTD-杭州圣隆生物科技有限公司

Home > Antibody > Primary Antibody > Anti-Cyclin G antibody

Anti-Cyclin G antibody

Total

Product Summary

Alias:CCNG 1; CCNG; CCNG1; CYCG1; Cyclin G; CCNG1_HUMAN; Cyclin-G; Cyclin G1; CyclinG1; Cyclin-G1.

NO.:SL25631R

Clonality:Polyclonal

React Species:Human,Mouse,Rat(predicted:Pig,Dog,Cow,Horse,Rabbit,Sheep)

concentration:1mg/ml

Applications:IHC-P,WB,IHC-F,IF

Manual

Product Spec:

50ul

100ul

200ul

Number:

Details

Product Name	Cyclin G
Chinese Name	周期素G抗体
Alias	CCNG 1; CCNG; CCNG1; CYCG1; Cyclin G; CCNG1_HUMAN; Cyclin-G; Cyclin G1; CyclinG1; Cyclin-G1.
Immunogen Species
Clonality	Polyclonal
React Species	Human,Mouse,Rat(predicted:Pig,Dog,Cow,Horse,Rabbit,Sheep)
Applications	WB=1:500-2000, IHC-P=1:100-500, IHC-F=1:100-500, IF=1:100-500 optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	34kDa
Cellular localization	The nucleus
Form	Lyophilized or Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from mouse Cyclin G: 251-344/344
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	1M TBS(pH7.4) with 1% BSA, 3% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	Cyclin G contains a typical N terminal cyclin box and a carboxy terminal domain sequence homologous to the tyrosine phosphorylation site of the epidermal growth factor receptor. Cyclin G2 shares 53% amino acid sequence identity with cyclin G1. Peak expression of cyclin G2 is seen in late S phase, as opposed to cyclin G1 expression, which is constitutive. Function: May play a role in growth regulation. Is associated with G2/M phase arrest in response to DNA damage. May be an intermediate by which p53 mediates its role as an inhibitor of cellular proliferation (By similarity). Subcellular Location: Nucleus. DNA replication foci after DNA damage. Tissue Specificity: High levels in skeletal muscle, ovary, kidney and colon. Similarity: Belongs to the cyclin family. Cyclin G subfamily. SWISS: P51945 Gene ID: 12450 Database links: Entrez Gene: 900 Human Omim: 601578 Human SwissProt: P51959 Human Unigene: 79101 Human Cyclin G的生物功能还没有完全清楚，他是Cyclin家族中近来发现的新成员，也是已知的唯一受到Tumour抑制基因p53调控的Cyclin。近年来经研究发现，Cyclin G可能有促进细胞增长的作用，在细胞增殖和神经再生中的可能起到一定的作用。
Product Picture	Paraformaldehyde-fixed, paraffin embedded (human breast carcinoma); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Incubation with (Cyclin G) Polyclonal Antibody, Unconjugated (SL25631R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining. Paraformaldehyde-fixed, paraffin embedded (human kidney); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Incubation with (Cyclin G) Polyclonal Antibody, Unconjugated (SL25631R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining. Paraformaldehyde-fixed, paraffin embedded (mouse kidney); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Incubation with (Cyclin G) Polyclonal Antibody, Unconjugated (SL25631R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining. Paraformaldehyde-fixed, paraffin embedded (rat brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Incubation with (Cyclin G) Polyclonal Antibody, Unconjugated (SL25631R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.

Partial purchase records (0)

No one bought this product