Vascular Endothelial Growth Factor 165 (VEGF), Human, Recombinant

Brief introduction:Vascular endothelial growth factor (VEGF) is a potent growth and angiogenesis cytokine. It stimulates endothelial cell proliferation and survival, promotes angiogenesis and vascular permeability. VEGF is expressed in vascularized tissues and plays an important role in normal and pathological angiogenesis. A large amount of evidence has shown that VEGF is involved in tumor metastasis and the occurrence of intraocular neovascularization syndrome. Vegf transmits signals through three receptors: FMS-like tyrosine kinase (flt-1), KDR gene products, and flt4 gene products.Recombinant Human Vascular endothelial Growth factor A165 (rhVEGF-A165) is a disulfide bonded dimer produced by Pichia pastoris and contains two polypeptide chains, each containing 165 amino acids. rhVEGF-A165 has biological activity with a molecular weight of 38.2kDa.· Vascular Endothelial Growth Factor 165 (VEGF), Human, RABBIT; VPF;  Folliculostellate cell-derived growth factor;  Glioma-derived endothelial cell mitogenPhysical properties and indexes:Purity: >95%Endotoxin: <0.5 EU/μgTiter: 2 x 105 -- 1 x 106 units/mgExpression host: P. pastorisSource: HumanPurification Method: purification by chromatographyCharacter: This product is white loose bodyStability: Freeze-dried powder can be stored at -70℃ for 12 months, dissolved liquid can be stored at -20℃ for 6 months, 4 weeks at 4℃, and avoid repeated freeze-thawAmino acid sequence:APMAEGGGQN HHEVVKFMDV YQRSYCHPIE TLVDIFQEYP DEIEYIFKPS CVPLMRCGGC CNDEGLECVP TEESNITMQI MRIKPHQGQH IGEMSFLQHN KCECRPKKDR  ARQENPCGPC SERRKHLFVQ DPQTCKCSCK NTDSRCKARQ LELNERTCRC DKPRR