Vascular Endothelial Growth Factor 164 (VEGF), Mouse, Recombinant

Brief introduction:Vascular endothelial growth factor (VEGF) is a potent growth and angiogenesis cytokine. It stimulates endothelial cell proliferation and survival, promotes angiogenesis and vascular permeability. VEGF is expressed in vascularized tissues and plays an important role in normal and pathological angiogenesis. A large amount of evidence has shown that VEGF is involved in tumor metastasis and the occurrence of intraocular neovascularization syndrome. Vascular endothelial growth factor signals through three receptors: FMS-like tyrosine kinase (flt-1), KDR gene product (the mouse KDR homolog is flk-1 gene product), and flt4 gene product.Recombinant Mouse vascular endothelial growth factor A164 (rmVEGF-A164) is a disulfide bonded homodimer produced by Pichia pastoris and contains two polypeptide chains, each containing 165 amino acids. rmVEGF-A164 has biological activity with a molecular weight of 39kDa.Vascular Endothelial Growth Factor 164 (VEGF), Mouse, RABBIT; VPF;  Folliculostellate cell-derived growth factor;  Glioma-derived endothelial cell mitogenPhysical properties and indexes:Purity: >95%Endotoxin: <1 EU/μgTiter: >1.7 x 105 units/mgExpression host: P. pastorisSource: MousePurification Method: purification by chromatographyCharacter: This product is white loose bodyStability: Freeze-dried powder can be stored at -70℃ for 12 months, dissolved liquid can be stored at -20℃ for 6 months, 4 weeks at 4℃, and avoid repeated freeze-thawAmino acid sequence:MAPTTEGEQK SHEVIKFMDV YQRSYCRPIE TLVDIFQEYP DEIEYIFKPS CVPLMRCAGC CNDEALECVP TSESNITMQI MRIKPHQSQH IGEMSFLQHS RCECRPKKDR  TKPEKHCEPC SERRKHLFVQ DPQTCKCSCK NTDSRCKARQ LELNERTCRC DKPRR