Proheparin-binding EGF-likegrowth factor(HB-EGF),Human,Recombinant

Brief introduction:Heparin binding epidermal growth factor-like growth factor (HB-EGF) is a member of the EGF family. HB-EGF is expressed in macrophages, monocytes, endothelial cells and muscle cells and is known as HB-EGF because of its strong affinity with heparin. It plays an important role in wound healing, myocardial hypertrophy, and heart development and function. The transmembrane form of HB-EGF is a unique receptor for diphtheria toxin and plays a role in signaling in cells. HB-EGF is involved in normal physiological and pathological processes, including tumor progression and metastasis, organ proliferation, and atherosclerotic disease. HB-EGF can bind to two sites on the cell surface, heparan sulfate proteoglycans and EGF receptors that influence interactions between cells.Recombinant human heparin binding epidermal growth factor-like growth factor (rmHB-EGF) is a polypeptide chain containing 86 amino acids with a molecular mass of 12-14kDa.Aliases: Proheparin-binding EGF-likegrowth factor(HB-EGF),Human,Recombinant; DTR; DTS; HEGFLPhysical properties and indexes:Purity: >95%Endotoxin: <0.2EU/μgTiter: >2x 106units/mgExpression host: CHOSource: HumanPurification Method: purification by chromatographyCharacter: This product is white loose bodyStability: The freeze-dried powder can be stored at -20℃ for 12 months, the dissolved liquid can be stored at -20℃ for 2 months, and at 4℃ for 1 week, and avoid repeated freeze-thawAmino acid sequence:DLQEADLDLL RVTLSSKPQA LATPNKEEHG KRKKKGKGLGKKRDPCLRKY KDFCIHGECK YVKELRAPSC ICHPGYHGERCHGLSL