Product Name：Collagen II Mouse mAb

Chinese Name:  Ⅱ型胶原α1蛋白/软骨钙素单克隆抗体

Alias:          ACG2; ANFH; ANFH1; AOM; COL11A3; EDMMD; LCPD; OSCDP; PLSDT; SEDC; SEDSTN; SEMDSTWK; SMDALG; STL1; VPED; Col2; Col2a; Col2a-1; Del1; Dmm; Lpk; M100413; Rgsc413; Rgsc856; CG2A1A; COLLII; CO2A1_HUMAN; COL2A1; Alpha-1 type II collagen; CO2A1_MOUSE; CO2A1_RAT;

Applications:

Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.

Reactivity:     Rat (predicted: Mouse)

Host:              Mouse

Immunogen:  KLH conjugated synthetic peptide derived from mouse Collagen II

Isotype:          IgG1, k

Form:             Liquid

Purification:  affinity purified by Protein G

Clonality:       Monoclonal

CloneNo.:       3G6

PredictedMW.: 142 kDa

Concentration:  1mg/ml

Buffer Solution: 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

SWISS:               P28481

Gene ID:             12824

Storage:        Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.

Attention:     This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

Database links:

Entrez Gene : 1280 Human

Entrez Gene : 12824 Mouse

Entrez Gene : 25412 Rat

Omim : 120140 Human

SwissProt : P02458 Human

SwissProt : P28481 Mouse

SwissProt : P05539 Rat

Unigene : 408182 Human

Unigene : 2423 Mouse

Unigene : 10124 Rat

Product Detail:

This gene encodes the alpha-1 chain of type II collagen, a fibrillar collagen found in cartilage and the vitreous humor of the eye. Mutations in this gene are associated with achondrogenesis, chondrodysplasia, early onset familial osteoarthritis, SED congenita, Langer-Saldino achondrogenesis, Kniest dysplasia, Stickler syndrome type I, and spondyloepimetaphyseal dysplasia Strudwick type. In addition, defects in processing chondrocalcin, a calcium binding protein that is the C-propeptide of this collagen molecule, are also associated with chondrodysplasia. There are two transcripts identified for this gene. [provided by RefSeq, Jul 2008]