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Rabbit Anti-RANBP17/AF647 Conjugated antibody

Rabbit Anti-RANBP17/AF647 Conjugated antibody
Total $596

Product Summary

Alias:Exp 7; Exp7; Exportin 7; Exportin7; KIAA0745; RAN binding protein 16; RANBP 16; XPO 7; XPO7.

NO.:SL21153R-AF647

Clonality:Polyclonal

Immunogen Species:Rabbit

React Species:(predicted:Human,Mouse,Rat,Pig,Cow,Horse,Rabbit,Sheep,GuineaPig,Chimpanzee)

Applications:ICC/IF,IF

concentration:1mg/ml

    Number:

Details

Product Name Anti-RANBP17/AF647
Chinese Name AF647标记的RANBinding protein17抗体
Alias Exp 7; Exp7; Exportin 7; Exportin7; KIAA0745; RAN binding protein 16; RANBP 16; XPO 7; XPO7.
Research Area Cell biology Signal transduction Binding protein G protein signal
Immunogen Species Rabbit
Clonality Polyclonal
React Species (predicted:Human,Mouse,Rat,Pig,Cow,Horse,Rabbit,Sheep,GuineaPig,Chimpanzee)
Applications ICC/IF=1:50-200,IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Molecular weight 124kDa
Form Lyophilized or Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human RANBP17
Lsotype IgG
Purification affinity purified by Protein A
Storage Buffer 1M TBS(pH7.4) with 1% BSA, 3% Proclin300 and 50% Glycerol.
Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 1M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail background:
The transport of protein and large RNAs through the nuclear pore complexes (NPC) is an energy-dependent and regulated process. The import of proteins with a nuclear localization signal (NLS) is accomplished by recognition of one or more clusters of basic amino acids by the importin-alpha/beta complex; see MIM 600685 and MIM 602738. The small GTPase RAN (MIM 601179) plays a key role in NLS-dependent protein import. RAN-binding protein-17 is a member of the importin-beta superfamily of nuclear transport receptors.[supplied by OMIM, Jul 2002]

Function:
May function as a nuclear transport receptor.

Subcellular Location:
Cytoplasm. Nucleus. Nucleus > nuclear pore complex.

Tissue Specificity:
Highly expressed in testis, moderately in pancreas and weakly in other tissues studied.

Similarity:
Belongs to the exportin family.

Database links:

Entrez Gene: 739299 Chimpanzee

Entrez Gene: 529222 Cow

Entrez Gene: 479293 Dog

Entrez Gene: 64901 Human

Entrez Gene: 100526145 Pig

Entrez Gene: 303029 Rat

Omim: 606141 Human

SwissProt: Q9H2T7 Human

Unigene: 410810 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

Partial purchase records (4)

UsernameQuantitybought time
Sa***22024-05-22
Ga***12023-07-30
He***22023-05-31
Ka***22023-05-22
Total 4 records, divided into1 pages. First Prev Next Last

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