Details
| Product Name | Anti-phospho-Kv4.2 (Thr607)/AF647 |
| Chinese Name | AF647标记的磷酸化电压门控性钾Channel proteinKv4.2抗体 |
| Alias | p-KCND2/Kv4.2(Thr607); p-Kv4.2(Thr607); Potassium voltage-gated channel subfamily D member 2; KCD2; KCND 2; KCND2; KCND2_HUMAN; KIAA1044; Potassium voltage gated channel Shal related subfamily member 2; RK 5; RK5; Voltage gated potassium channel Kv4.2; Voltage gated potassium channel subunit Kv4.2; Voltage sensitive potassium channel; voltage-gated potassium channel Kv4.2; Voltage-gated potassium channel subunit Kv4.2; voltage-sensitive potassium channel. |
| Product Type | Phosphorylated anti |
| Research Area | Cardiovascular Neurobiology Channel protein |
| Immunogen Species | Rabbit |
| Clonality | Polyclonal |
| React Species | Rat(predicted:Human,Mouse,Pig,Cow,Rabbit) |
| Applications | IF=1:100-500
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| Molecular weight | 70kDa |
| Form | Lyophilized or Liquid |
| Concentration | 1mg/ml |
| immunogen | KLH conjugated synthesised phosphopeptide derived from human KCND2 around the phosphorylation site of Thr607 |
| Lsotype | IgG |
| Purification | affinity purified by Protein A |
| Storage Buffer | 1M TBS(pH7.4) with 1% BSA, 3% Proclin300 and 50% Glycerol. |
| Storage | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 1M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| Product Detail |
background: Voltage-gated K+ channels in the plasma membrane control the repolarization and the frequency of action potentials in neurons, muscles, and other excitable cells. Pore-forming (alpha) subunit of voltage-gated rapidly inactivating A-type potassium channels. May contribute to I(To) current in heart and I(Sa) current in neurons. Channel properties are modulated by interactions with other alpha subunits and with regulatory subunits. Function: Pore-forming (alpha) subunit of voltage-gated rapidly inactivating A-type potassium channels. May contribute to I(To) current in heart and I(Sa) current in neurons. Channel properties are modulated by interactions with other alpha subunits and with regulatory subunits. Subunit: Homotetramer or heterotetramer with KCND1 and/or KCND3. Interacts with DPP6, DLG4 and NCS1/FREQ (By similarity). Interacts with DLG1. Associates with the regulatory subunits KCNIP1, KCNIP2, KCNIP3 and KCNIP4. Probably part of a complex consisting of KCNIP1, KCNIP2 isoform 3 and KCND2. The KCND2-KCNIP2 channel complex contains four KCND2 and four KCNIP2 subunits. Interacts with FLNA, FLNC and DPP10. Subcellular Location: Cell membrane. Cell projection > dendrite. Detected in dendrites in cultured hippocampal neurons. Association with KCNIP2 probably enhances cell surface expression. Tissue Specificity: Highly expressed throughout the brain. Expression is very low or absent in other tissues. Post-translational modifications: Phosphorylated on serine and threonine residues. Similarity: Belongs to the potassium channel family. D (Shal) (TC 1.A.1.2) subfamily. Kv4.2/KCND2 sub-subfamily. Database links: Entrez Gene: 3751 Human Omim: 605410 Human SwissProt: Q9NZV8 Human Unigene: 654739 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
Partial purchase records (2)
| Username | Quantity | bought time |
| Ja*** | 1 | 2024-05-25 |
| Mi*** | 2 | 2023-11-14 |
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