Details
| Product Name | Anti-AKR1C2/AF647 |
| Chinese Name | AF647标记的胆汁酸Binding proteinDDH2抗体 |
| Alias | 2-dihydrobenzene-1; 2-diol dehydrogenase; 3 alpha HSD3; 3 alpha hydroxysteroid dehydrogenase type III; 3-alpha-HSD3; AK1C2_HUMAN; AKR1C pseudo; AKR1C2; Aldo keto reductase family 1 member C2; Aldo-keto reductase family 1 member C2; BABP; Bile acid binding protein; Chlordecone reductase homolog; Chlordecone reductase homolog HAKRD; DD; DD-2; DD/BABP; DD2; DDH 2; DDH2; Dihydrodiol dehydrogenase 2; Dihydrodiol dehydrogenase/bile acid binding protein; Dihydrodiol dehydrogenase/bile acid-binding protein; HAKRD; HBAB; MCDR 2; MCDR2; Pseudo chlordecone reductase; Trans 1 2 dihydrobenzene 1 2 diol dehydrogenase; Trans-1; Type II dihydrodiol dehydrogenase; Type III 3 alpha hydroxysteroid dehydrogenase; Type III 3-alpha-hydroxysteroid dehydrogenase. |
| Research Area | Tumour Cell biology Signal transduction TumourCell biologyMaker |
| Immunogen Species | Rabbit |
| Clonality | Polyclonal |
| React Species | Rat(predicted:Human,Mouse) |
| Applications | IF=1:100-500
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| Molecular weight | 37kDa |
| Form | Lyophilized or Liquid |
| Concentration | 1mg/ml |
| immunogen | KLH conjugated synthetic peptide derived from human AKR1C2 |
| Lsotype | IgG |
| Purification | affinity purified by Protein A |
| Storage Buffer | 1M TBS(pH7.4) with 1% BSA, 3% Proclin300 and 50% Glycerol. |
| Storage | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 1M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| Product Detail |
background: Works in concert with the 5-alpha/5-beta-steroid reductases to convert steroid hormones into the 3-alpha/5-alpha and 3-alpha/5-beta-tetrahydrosteroids. Catalyzes the inactivation of the most potent androgen 5-alpha-dihydrotestosterone (5-alpha-DHT) to 5-alpha-androstane-3-alpha,17-beta-diol (3-alpha-diol). Has a high bile-binding ability. Function: Works in concert with the 5-alpha/5-beta-steroid reductases to convert steroid hormones into the 3-alpha/5-alpha and 3-alpha/5-beta-tetrahydrosteroids. Catalyzes the inactivation of the most potent androgen 5-alpha-dihydrotestosterone (5-alpha-DHT) to 5-alpha-androstane-3-alpha,17-beta-diol (3-alpha-diol). Has a high bile-binding ability. Subcellular Location: Cytoplasm (Potential). Tissue Specificity: Expressed in fetal testes. Expressed in fetal and adult adrenal glands. DISEASE: Defects in AKR1C2 are a cause of 46,XY sex reversal type 8 (SRXY8) [MIM:614279]. A disorder of sex development. Affected individuals have a 46,XY karyotype but present as phenotypically normal females. Similarity: Belongs to the aldo/keto reductase family. Database links: SwissProt: P52895 Human SwissProt: Q04828 Human
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
Partial purchase records (4)
| Username | Quantity | bought time |
| Um*** | 2 | 2024-06-11 |
| Wi*** | 1 | 2024-06-07 |
| Be*** | 1 | 2024-05-05 |
| La*** | 1 | 2023-12-15 |
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