Details
| Product Name | Anti-NKG2D/PE-Cy3 |
| Chinese Name | PE-Cy3标记的NK细胞受体2D抗体 |
| Alias | KLRK1; natural killer cell group 2D; NKG2-D isoform b; Klrk1; Nkrp2; NKG2-D type II integral membrane protein; NKG2-D-activating NK receptor; NK cell receptor D; Killer cell lectin-like receptor subfamily K; NK lectin-like receptor; CD314; CD314 antigen; D12S2489E; Killer cell lectin like receptor subfamily K member 1; Killer cell lectin-like receptor subfamily K member 1; KLR; Klrk1; NKG2 D activating NK receptor; NKG2 D type II integral membrane protein; NKG2-D-activating NK receptor; Nkg2d; NKG2D_HUMAN; NKLLR; NKR P2; Nkrp2. |
| Research Area | Cell biology immunology |
| Immunogen Species | Rabbit |
| Clonality | Polyclonal |
| React Species | Mouse, Rat, (predicted: Human, Pig, ) |
| Applications | Flow-Cyt=1:50-200 ICC=1:50-200 IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| Molecular weight | 25kDa |
| Form | Lyophilized or Liquid |
| Concentration | 1mg/ml |
| immunogen | KLH conjugated synthetic peptide derived from human NKG2D |
| Lsotype | IgG |
| Purification | affinity purified by Protein A |
| Storage Buffer | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| Storage | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| Product Detail |
background: This locus represents naturally occurring read-through transcription between the neighboring KLRC4 (killer cell lectin-like receptor subfamily C, member 4) and KLRK1 (killer cell lectin-like receptor subfamily K, member 1) genes on chromosome 12. The read-through transcript includes an alternate 5' exon and lacks a significant portion of the KLRC4 coding sequence, including the start codon, and it thus encodes the KLRK1 protein. [provided by RefSeq, Dec 2010] Function: Receptor for MICA, MICB, ULBP1, ULBP2, ULBP3 (ULBP2>ULBP1>ULBP3) and ULBP4. Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. Involved in the immune surveillance exerted by T- and B-lymphocytes. Subunit: Homodimer. Subcellular Location: Membrane; Single-pass type II membrane protein. Tissue Specificity: Natural killer cells. Expressed on essentially all CD56+CD3- NK cells from freshly isolated PBMC. Also detected in gamma-delta cells and CD8+ alpha-beta T-cells. Expressed in interferon-producing killer dendritic cells (IKDCs). Similarity: Contains 1 C-type lectin domain. Database links: Entrez Gene: 100528032 Human Entrez Gene: 22914 Human Entrez Gene: 27007 Mouse Omim: 611817 Human SwissProt: P26718 Human SwissProt: O54709 Mouse Unigene: 387787 Human Unigene: 8217 Mouse Unigene: 14544 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. NKG2-D出现在免疫细胞上表达的受体，NKG2D属C型凝集素家族Transmembrane protein，广泛表达在NK细胞、CD8+的αβT细胞和γδT细胞表面，可以提高NK细胞对Tumour细胞的杀伤活性。 |
Partial purchase records (4)
| Username | Quantity | bought time |
| Ni*** | 1 | 2024-05-27 |
| Ad*** | 2 | 2024-05-19 |
| Ja*** | 2 | 2024-03-26 |
| Be*** | 1 | 2023-07-09 |
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