Rat IL-18 ELISA Kit is on line for Sunlong Medical
2024-01-18
IL-18, produced by macrophages, can cooperate with IL-12 to induce the expression of TNF-α, promote the occurrence of arthritis and the proliferation of synovial tissue. IL-18 stimulates the expression of iNOS, COX-2, IL-6 and other genes in articular chondrocytes, and induces the production of a large number of NO and PGE2, which participate in joint inflammation, injury and degeneration. IL-18 can induce chondrocytes to produce MMP-1, MMP-3, MMP-13 and promote the degradation of cartilage tissue. In addition, studies have confirmed that IL-18 up-regulates the expression of TNF receptor, VCAM-1 and ICAM-1 through NF-κB and PI3K pathways, thereby promoting the production of TNF-α by mononuclear cells/macrophages.
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Cat NO.:
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EL0043Ra |
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Product:
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Sunlong Medical™ Rat IL-18 ELISA Kit |
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Storage
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4℃ (unopened) for two years |
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Shipping Condition
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4℃ |
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Sample Type:
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Serum | plasma | cell culture supernatant and other biological samples |
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Spike Recovery Range:
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86% - 119% |
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Mean Spike Recovery:
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1 |
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CV of Intra plate:
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3.3% - 4.8% |
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CV of Inter plate:
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3.5% - 5.3% |
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NCBI_Gene:
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29197 |
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UniProtKB:
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P97636 |
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